PyMeshLab is a Python library that provides bindings to the core functionality of MeshLab, a mature C++ application for processing and editing large 3D triangle meshes and point clouds. The library exposes a MeshSet class that wraps hundreds of geometry processing filters (e.g., simplification, smoothing, Boolean operations, surface reconstruction, parameterization) via a dynamic method registration pattern—each filter becomes an method on MeshSet at import time. The architecture relies on a pybind11-based C++ extension module that communicates with MeshLab's filter plugins, VCG library, Eigen, and Qt. Users can load meshes in many standard formats (OBJ, PLY, STL, etc.), apply filters with typed parameters (including custom types like PercentageValue and Color), and export results. The project includes comprehensive documentation, automated tests with sample meshes, and cross-platform build scripts for Linux, macOS, and Windows. While the library is tightly coupled to the MeshLab submodule, its design patterns—such as dynamic filter registration and reusable parameter wrappers—demonstrate solid engineering for bridging C++ and Python.