This repository is a curated collection of 177+ domain-specific scientific 'skills' for AI agents, following the Agent Skills standard. Each skill is a self-contained module providing a CLI tool, documentation, and tests for a specific scientific or technical task—ranging from single-cell RNA-seq analysis (scanpy) and molecular docking (diffdock) to clinical report validation and ISO standards readiness. The architecture is a monorepo of independent skills, each with its own scripts/, references/, assets/, and tests/. Skills are designed to be safe, bounded, and reproducible: they validate inputs before execution, enforce resource limits, avoid network access unless explicitly required, and produce structured JSON reports. The repository also includes a shared test infrastructure (skill_contract) and a meta-skill (autoskill) that can automatically propose new skills from screen activity. While primarily an application library for AI agents, it has strong data/research characteristics due to its heavy use of scientific data formats and validation of research artifacts.

Mimeo is a Python CLI application that transforms a named expert's public body of work (essays, talks, interviews, podcasts, papers, etc.) into a structured, source-verified Agent Skill file (SKILL.md) and/or AGENTS.md, designed for AI coding agents to adopt the expert's reasoning style. The pipeline orchestrates identity resolution, source discovery via the Parallel API, content fetching (web, YouTube transcripts, optional audio transcription), LLM-based distillation and clustering (via OpenRouter), quote verification against source text, structured skill authoring, critique/refinement loops, and optional avatar generation. The output is a curated set of markdown files (principles, frameworks, mental models, anti-patterns, heuristics, quotes) organized per expert in the `output/` directory. The codebase is well-architected with async stages, a fingerprint-based caching layer, SSRF-safe HTTP helpers, prompt injection mitigations, and extensive offline tests using fake LLM/Parallel clients. While the primary purpose is the application tool, the generated output forms a reusable knowledge base of expert reasoning patterns, giving the repo a hybrid character.